Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2010-11-19
2011-12-06
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S108000
Reexamination Certificate
active
08071612
ABSTRACT:
The present invention provides compounds of formula (I) and compounds of formula (VII-a) as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitorswherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rdand X have defined meanings.
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patent: WO 02/36599 (2002-05-01), None
PCT Intl. Search Report, PCT/EP2004/013163,Apr. 20, 2005.
Li et al., “PARP Inhibitors”,IDrugs, 2001, pp. 804-812, vol. 4, No. 7, Current Drugs Ltd., GB.
Weltin et al., “Effect of 6(5-Phenanthridinone, an Inhibitor of Poly(ADP-ribose) Polymerase, on Cultured Tumor Cells”,Oncology Research, 1994, pp. 399-403, Vo.l. 6, No. 9, El Sevier Ltd., USA.
Guillemont Jérôme Emile Georges
Mabire Dominique Jean-Pierre
Somers Maria Victorina Francisca
Van Dun Jacobus Alphonsus Josephus
Wouters Walter Boudewijn Leopold
Janssen Pharmaceutica NV
McDowell Brian
Wilson James O
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