6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S354000, C546S157000

Reexamination Certificate

active

07855207

ABSTRACT:
The present invention provides compounds of formula (I) and compounds of formula (VII-a) as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitorswherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rdand X have defined meanings.

REFERENCES:
patent: 5028606 (1991-07-01), Venet et al.
patent: 5177075 (1993-01-01), Suto et al.
patent: 0371564 (1990-06-01), None
patent: WO 02/36599 (2002-05-01), None
patent: WO 2004/043950 (2004-05-01), None
Ali et al., Synthesis and Antimicrobial Activities of Some Novel Quinoxalinone Derivatives, 2000, Molecules, 5, 864-873.
Pailer et al., Synthesis of quinoxalone derivatives, 1962, Monatshefte fuer Chemie,93, 1005-1018.
Borisy et al. Systematic discovery of multicomponent therapeutics. 2003, Proceedings of the National Academy of Sciences of the United States of America, 100, 7977-7982.
Li et al., “PARP Inhibitors”,IDrugs, 2001, pp. 804-812, vol. 4, No. 7, Current Drugs Ltd., GB.
Weltin et al., “Effect of 6(5-Phenanthridinone, an Inhibitor of Poly(ADP-ribose) Polymerase, on Cultured Tumor Cells”,Oncology Research, 1994, pp. 399-403, vol. 6, No. 9, El Sevier Ltd., USA.
PCT Intl. Search Report, PCT/EP2004/013163,Apr. 20, 2005.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4165964

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.