6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and

Details 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and

1994-03-28

1996-04-09

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546101, C07D41914, A61K 3147

Patent

active

055062326

ABSTRACT:
In the search for novel heteroanalogs of anthracendiones, 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate salt (BBR 2778), was selected as the most promising compound. New methods of synthesis produce the compound in purity greater than 99%.

REFERENCES:
Krapcho et al, J. Med. Chem, vol. 28, pp. 1124-1126, 1985.
Krapcho et al., J. Med Chem, vol. 37, pp. 828-837, 1994.

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