Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1997-07-10
2000-04-04
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514182, 514825, 514826, 540 61, 552530, 552533, A61K 3156, C07J 1300, C07J 7100
Patent
active
060461853
ABSTRACT:
Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stereochemistries such as 6.alpha. and 7.beta. oxygen substitution, and an alpha hydrogen at the 5 position in addition to having 6.alpha. and 7.beta. oxygen substitution. Steroids having 3,4-epoxy functionality are also disclosed. In addition, steroids having C17 pyran and .delta.-lactone functionality, with oxygen substitution at C6 and C7, or at C15, of the steroid nucleus, are disclosed.
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Burgoyne David L.
Chau Joseph H.-L.
Langlands John M.
Piers Edward
Rogers Christine
Badio Barbara
Dees Jos,e G.
Inflazyme Pharmaceuticals Ltd.
The University of Alberta
The University of British Columbia
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