6,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones

Details 6,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones 6,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones

1983-09-06

1987-02-10

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48712

Patent

active

046423451

ABSTRACT:
Imidazopyrimidinones and other diazaheterocyclopyrimidinones having an additional fused imidazole or triazole ring have utility as bronchodilators, mediator release inhibitors, phosphodiesterase inhibitors, and peripheral vasodilators. They are orally active and useful in the prophylaxis and treatment of asthma. A preferred compound is 4-[(4-chlorophenyl)methyl]-6,7-dihydro-3H-imidazo[1,2-a]-purin-9(4H)-one.

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