6,7-Didehydro-PGI.sub.1 compounds

Details 6,7-Didehydro-PGI.sub.1 compounds 6,7-Didehydro-PGI.sub.1 compounds

1977-12-15

1978-12-05

Jiles, Henry R.

Harness for working animal

542429, 544131, 544153, 544376, 544364, 2602444, 26032636, 26034622, 26034673, 546269, 546256, 546194, 546196, C07D30793

Patent

active

041287134

ABSTRACT:
This invention relates to certain structural and pharmacological analogs of 5,6-dihydroprostacyclin (PGI.sub.1) wherein an endocyclic double bond is present at the C-6 to C-7 position. These novel unsaturated prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin is used, e.g., as antithrombotic agents, smooth muscle stimulators, gastric antisecretory agents, antihypertensive agents, antiasthma agents, nasal decongestants, or regulators of fertility and procreation.

REFERENCES:
johnson et al., Prostaglandins 12, 915, (1976).

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