6,7-Didehydro- or 7,8-didehydro-PGI.sub.1 acyl-substituted pheny

Details 6,7-Didehydro- or 7,8-didehydro-PGI.sub.1 acyl-substituted pheny 6,7-Didehydro- or 7,8-didehydro-PGI.sub.1 acyl-substituted pheny

1979-06-14

1980-11-25

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

542426, 542429, C07D307935

Patent

active

042357888

ABSTRACT:
The present invention relates to novel acyl-substituted esters of 6,7-didehydro- or 7,8-didehydro-PGI.sub.1 compounds, e.g., the 4-acetylphenyl ester of such PGI.sub.1 analogs. These esters are characterized by pharmacological activity, being for example useful for the pharmacological purposes for which the corresponding free acids are employed.

REFERENCES:
Johnson et al., J. Am. Chem. Soc. 99, 4182 (1977).

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