6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives

Details 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives

1982-12-27

1985-04-09

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548427, 548451, A61K 3140, C07D20956

Patent

active

045101574

ABSTRACT:
Herein is disclosed compounds of the formula ##STR1## in which R.sup.1,R.sup.2,R.sup.3,R.sup.4 and R.sup.5 each is hydrogen or lower alkyl, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the compounds and pharmaceutical compositions. The compounds exhibit dopamine-receptor stimulating activity in a mammal and are useful for treating hyperprolactinemia, galactorrhea, amenorrhea, impotence, Parkinsonism, diabetes, acromegaly, hypertension and other central nervous system disorders.

REFERENCES:
patent: 3845073 (1971-10-01), Newberry
patent: 4110339 (1978-08-01), Bach et al.
patent: 4212804 (1980-07-01), Coppola
patent: 4370341 (1983-01-01), Asselin et al.
L. B. Shagalov et al., Chem. Abstr. 91, 56747 v, (1979), for Khim. Geterotsikl. Soedin, (3), 360, (1979).
L. B. Shagalov et al., Chem. Abstr. 89, 146703 r, (1978) for Khim. Geterotsikl. Soedin, (5), 634, (1978).
M. Mottet, Chem. Abstr. 69, 106400 v, (1968), for Ann. Sci. Univ. Besancon, Chim. 1967, (3), No. 4, 29 pp.

Affiliated with

Also associated with

Rating

6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1169361