6,5-fused aromatic ring systems having enhanced phosphodiesteras

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514243, 514247, 514248, 514249, 514300, 514302, 514303, 544184, 544236, 544264, 544278, 544280, 544179, 546113, 546115, 546118, A61K 3140, A61K 31435, C07D47104, C07D49804

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active

060750162

ABSTRACT:
Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE V inhibition. The present invention includes compounds of Formula I: ##STR1##

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