6-5, 6-6, or 6-7 Heterobicycles as factor Xa inhibitors

Details 6-5, 6-6, or 6-7 Heterobicycles as factor Xa inhibitors 6-5, 6-6, or 6-7 Heterobicycles as factor Xa inhibitors

2006-02-14

2006-02-14

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S141000

Reexamination Certificate

active

06998408

ABSTRACT:
The present application describes 6–5, 6—6, or 6–7 heterobicycles of Formula I or pharmaceutically acceptable salt forms thereof:wherein ring P is a 6-membered heteroaromatic and ring M is a 5-, 6-, or 7-membered non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

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