Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-02
2007-10-02
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S121000
Reexamination Certificate
active
10508306
ABSTRACT:
The present invention relates to 6-(4-substituted-anilino)pyrimidine derivatives useful as an antiviral agent, and more particularly novel 6-(4-substituted-anilino)pyrimidine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus; HCV), represented by the following formula I:in which R represents a C1-C4straight or branched alkoxycarbonyl group, heterocycliccarbonyl group or carboxyalkyl group; and pharmaceutically acceptable salts thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an effective ingredient. The 6-(4-substituted-anilino)pyrimidine derivatives according to the present invention have an excellent inhibitory effect on replication of Hepatitis C virus (HCV) and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C.
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Chisari, Nature, vol. 436, No. 18, Aug. 2005, pp. 930-932.
Firpi et al., Liver Transpl. Jan. 2003; 9(1); 57-61.
Han Jae-Jin
Kim Jong-Woo
Lee Geun-Hyung
Lee Sang-Wook
Park Eul-Yong
Anderson Rebecca
B & C Biopharm
Blackwell Sanders LLP
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