6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]-amino]acyl penicillin

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424271, C07D49964, C07D49966, C07D49968, C07D49970

Patent

active

041682661

ABSTRACT:
6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]amino]acyl pencillins which have the formula ##STR1## wherein R is hydrogen, lower alkyl, tri(lower alkyl)silyl, tri(lower alkyl)stannyl, trihaloethyl or a salt forming ion; R.sub.1 is hydrogen, lower alkyl, saturated or unsaturated cycloalkyl, phenyl, phenyl-lower alkyl, substituted phenyl or certain heterocyclic groups; R.sub.2 is hydrogen or methoxy; R.sub.3 is hydrogen, lower alkyl, phenyl-lower alkyl or cycloalkyl; and R.sub.4 and R.sub.5 each is hydrogen or lower alkyl, are useful as antibacterial agents.

REFERENCES:
patent: 3573294 (1971-03-01), Long et al.
patent: 3997533 (1976-12-01), Kabbe
patent: 4009272 (1977-02-01), Konig et al.
patent: 4028354 (1977-06-01), Breuer et al.
patent: 4073783 (1978-02-01), Hamanaka et al.

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