Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-05-30
1979-09-18
Schwartz, Gerald A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424271, C07D49964, C07D49966, C07D49968, C07D49970
Patent
active
041682661
ABSTRACT:
6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]amino]acyl pencillins which have the formula ##STR1## wherein R is hydrogen, lower alkyl, tri(lower alkyl)silyl, tri(lower alkyl)stannyl, trihaloethyl or a salt forming ion; R.sub.1 is hydrogen, lower alkyl, saturated or unsaturated cycloalkyl, phenyl, phenyl-lower alkyl, substituted phenyl or certain heterocyclic groups; R.sub.2 is hydrogen or methoxy; R.sub.3 is hydrogen, lower alkyl, phenyl-lower alkyl or cycloalkyl; and R.sub.4 and R.sub.5 each is hydrogen or lower alkyl, are useful as antibacterial agents.
REFERENCES:
patent: 3573294 (1971-03-01), Long et al.
patent: 3997533 (1976-12-01), Kabbe
patent: 4009272 (1977-02-01), Konig et al.
patent: 4028354 (1977-06-01), Breuer et al.
patent: 4073783 (1978-02-01), Hamanaka et al.
Breuer Hermann
Treuner Uwe D.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Schwartz Gerald A.
Smith Merle J.
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