6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives

Details 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives

1981-12-23

1985-05-07

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 96, 549354, C07D31300, A61K 3142, A61K 31335

Patent

active

045159467

ABSTRACT:
This invention relates to 6,11-dihydro-11-oxo-dibenz[b,e]oxepin derivatives of the formula ##STR1## where Y is alkyl, alkoxy, halogen or trifluoromethyl, n is 0, 1, 2 or 3; R is ##STR2## where Hal is a halogen; ##STR3## where n is 0, 1, 2 or 3; p is 1 or 2; q is 0, 1, or 2; R.sup.1 to R.sup.7 are the same or different and are hydrogen and alkyl and R.sup.8 is hydrogen, alkyl and phenyl; and R.sup.9 is alkyl and the pharmaceutically acceptable acid addition salts thereof.

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patent: 4350519 (1982-09-01), Durr
patent: 4356186 (1982-10-01), Uno et al.
Journ. Med. Chem., 20 (1), pp. 66-70 (1977).
Yoshioka et al., Journ. Med. Chem. (1978), vol. 21, No. 7, pp. 633-639.

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