6-(1'-Hydroxyethyl)-3-substituted

Details 6-(1'-Hydroxyethyl)-3-substituted 6-(1'-Hydroxyethyl)-3-substituted

1980-07-11

1984-01-03

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

2602452T, 424200, 4242485, 42424853, 42424855, 424250, 424267, 544 80, 544121, 544130, 544357, 544364, 544373, 546187, 546200, 546272, C07D48704, C07D20508, A61K 3140, A61K 31495

Patent

active

044242301

ABSTRACT:
Disclosed are 6-(1'-hydroxyethyl)-3-substituted ##STR1## wherein R' and R" are independently selected from H, substituted and unsubstituted alkyl and aralkyl groups, or together form a substituted or unsubstituted cyclic group. Such compounds and their O- and carboxyl derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4217453 (1980-08-01), Christensen et al.
Morrison et al.: Organic Chemistry, p. 727 (1969).
Thielheimer; Synthetic Methods, vol. 11:496 (1956).

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