6-(1,8-Naphthyridin-2-yl)-dithiino[1,4][2,3-c]-pyrroles useful a

Details 6-(1,8-Naphthyridin-2-yl)-dithiino[1,4][2,3-c]-pyrroles useful a 6-(1,8-Naphthyridin-2-yl)-dithiino[1,4][2,3-c]-pyrroles useful a

1983-04-21

1985-10-29

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544362, 544373, C07D40114, A61K 31495

Patent

active

045501106

ABSTRACT:
New compounds of the formula ##STR1## wherein X represents hydrogen, halogen, alkyl (1 to 4 C), alkoxy (1 to 4 C), cyano or nitro, R represents hydrogen, alkyl (1 to 4 C) [unsubstituted or substituted by 1, 2 or 3 halogens, alkenyl (2 to 4 C), alkynyl (2 to 4 C) or alkoxy (1 to 4 C)], phenyl [unsubstituted or substituted by 1, 2 or 3 halogens, alkyl (1 to 4 C), alkoxy (1 to 4 C), nitro or trifluoromethyl] or phenylalkyl (1 to 4 C) or phenylalkynyl (2 to 4 C) in which the phenyl radicals are optionally substituted as indicated above, Z represents an oxygen or sulphur atom, and one of m and p represents the figure O and the other the figure 1.
The new compounds are therapeutically useful, more particularly as tranquillizers and anticonvulsants.

REFERENCES:
patent: 4220646 (1980-09-01), Cotrel et al.
Wolff, M. E., "Burger's Medicinal Chemistry", Part I, 4 ed., (1980), pp. 169-171, John Wiley & Sons, N.Y.

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