Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1974-04-08
1981-03-03
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546 89, 544126, 544 586, 544375, 424256, 42424854, 424250, A61K 3154, C07D491052, A61K 31435, A61K 31495
Patent
active
042541166
ABSTRACT:
5H-[1]Benzopyrano[3,4-d]pyridines represented by the formula ##STR1## wherein each R.sub.1 is loweralkyl, R.sub.2 is alkyl, cycloalkyl or ##STR2## wherein Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms and each R.sub.4, R.sub.5 and R.sub.6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and R.sub.3 is hydroxy, acyloxy, loweralkoxy, loweralkenyloxy, loweralkynyloxy or ##STR3## X is a straight or branched chain alkylene group having from one to eight carbon atoms, and wherein R.sub.7 and R.sub.8 are the same or different members of the group consisting of hydrogen or loweralkyl, or ##STR4## wherein X is a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH.sub.2, O, S or NR.sub.10 with R.sub.10 being hydrogen or loweralkyl, with the limitation that when Z is O or S, the sum of a and b is 3 or 4; and when Z is NR.sub.10, the sum of a and b is 3-5; R.sub.9 is hydrogen or loweralkyl, and the pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 3429889 (1969-02-01), Shulgin
patent: 3514464 (1970-05-01), Pars et al.
patent: 3632595 (1972-01-01), Pars et al.
patent: 3661919 (1972-05-01), Razdan et al.
patent: 3787424 (1974-01-01), Pars et al.
Abbott Laboratories
Jiles Henry R.
Niblack Robert L.
Whittenbaugh Robert C.
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