53 human secreted proteins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C530S350000, C530S300000, C435S007100, C435S069100, C514S002600

Reexamination Certificate

active

07026447

ABSTRACT:
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

REFERENCES:
patent: WO-WO99/14328 (1999-03-01), None
Wells et al., Biochemistry, vol. 29, pp. 8509-8517, 1990.
U.S. Appl. No. 09/912,293, not published, Rosen et al.
U.S. Appl. No. 09/912,292, not published, Rosen et al.
Chai Z, Brereton P, Suzuki T, Sasano H, Obeyesekere V, Escher G, Saffery R, Fuller P, Enriquez C, Krozowski Z, “17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells ” Endocrinology. 2003 May;144(5):2084-91.
Brereton P, Suzuki T, Sasano H, Li K, Duarte C, Obeyesekere V, Haeseleer F, Palczewski K, Smith I, Komesaroff P, Krozowski Z. “Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung” Mol Cell Endocrinol. Jan. 2001 22;171(1-2):111-7.

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