5′-modified bicyclic nucleic acid analogs

Details 5′-modified bicyclic nucleic acid analogs 5′-modified bicyclic nucleic acid analogs

2007-05-10

2009-06-16

Lewis, Patrick T (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S042000, C514S043000, C536S022100

Reexamination Certificate

active

07547684

ABSTRACT:
The present invention provides 5′-modified bicyclic nucleoside analogs and oligomeric compounds comprising at least one of these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 5′-carbon. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including for example enhanced nuclease resistance.

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