5-trifluormethoxy-2-benzimidazolamine compounds

Details 5-trifluormethoxy-2-benzimidazolamine compounds 5-trifluormethoxy-2-benzimidazolamine compounds

1990-02-16

1991-09-17

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548239, C07D23530, A61K 31415

Patent

active

050495747

ABSTRACT:
5-Trifluoromethoxy-2-benzimidazolamine and its salts with an inorganic or organic acid, its preparation and medicinal products containing it.

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L-Glutamate, excitatory amino acid receptors and brain function, Graham E. Fagg, TINS, May 1985, pp. 207-209.
Excitatory Amino Acid Receptors in the Vertebrate Central Nervous System, Collingridge, et al., Pharmacological Reviews, vol. 40, No. 2, pp. 143-145, 193-195.
Frontal Cortical and Left Temporal Glutamatergic Dysfunction in Schizophrenia, Deakin, et al., J. Neurochem. 52, 1781-1786 (1989).
Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia, Graham et al., Neuroscience Letters 110 (1990), 124-130.

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