5-Sulfamoyl-orthanilic acids and process for their preparation

Details 5-Sulfamoyl-orthanilic acids and process for their preparation 5-Sulfamoyl-orthanilic acids and process for their preparation

1978-04-26

1979-07-17

Randolph, John D.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

424275, 2602396, 26023965, A61K 3134, A61K 3138, C07D30752, C07D33320

Patent

active

041615336

ABSTRACT:
Salidiuretically-active 5-Sulfamoyl-orthanilic acids and their salts, substituted in 4-position by halogen, methyl, phenoxy or phenylthio and by furyl or thienyl at the nitrogen atom, are disclosed, as is and a process for their manufacture by reacting a furyl- or thienyl-substituted amine with corresponding halogen-substituted benzene derivatives.

REFERENCES:
patent: 3356692 (1967-12-01), Horstmann et al.
patent: 3454562 (1969-07-01), Loev et al.
patent: 3875150 (1975-04-01), Feit et al.
Crossley et al., J. Am. Chem. Soc., vol. 60, pp. 2217 to 2222 (1938).

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