5-Substituted pyrimidine derivatives active against internal ani

Details 5-Substituted pyrimidine derivatives active against internal ani 5-Substituted pyrimidine derivatives active against internal ani

1980-02-05

1984-07-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544298, 544301, 544311, 544312, 544316, 544318, 544319, 544321, A61K 31505, C07D23934

Patent

active

044605889

ABSTRACT:
The invention concerns a process for killing internal parasites, especially trematodes or nematodes, affecting warm blooded animals such as cattle, sheep and goats by administering an effective amount of a composition containing as active ingredient a compound of the formula ##STR1## Certain of the compounds of formula I are novel and in further embodiments the invention provides novel compounds and compositions for use in the process of the invention. The process of the invention is especially applicable to the tretment of warm blooded animals infected with the trematodes Fasciola hepatica (liver fluke).

REFERENCES:
patent: 3896235 (1975-07-01), Harfeinst
patent: 4001234 (1977-01-01), Johnston
Frosyth, et al., "Chemical Abstracts", vol. 94, col. 94:103414h, 1981.
"Arzneimittel", Band 5, Teil, 2, 1972, pp. 37,98,99,109,190,191.
Kijima, et al., "Chemical Abstracts", vol. 93, col. 150268c.
Jojima, et al., "Agr. Biol. Chem.", vol. 30, No. 9, 1966, pp. 896-905.

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