5-Substituted pyranone compounds and their use as pharmaceutical

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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424283, 549416, 549419, 549420, 548251, 548252, 548253, 564218, 564341, 564342, 564347, 564384, A61K 3134, A61K 3135, C07D30932

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043649564

ABSTRACT:
Compounds are described of the formula ##STR1## in which R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano, 5-tetrazolyl or 5-tetrazolylaminocarbonyl, where R.sup.5 is hydrogen or C.sub.1-6 alkyl; R.sup.2 is hydrogen or C.sub.1-6 alkyl; R.sup.3 is a group of the formula

REFERENCES:
patent: 4060533 (1977-11-01), Nadelson
patent: 4065290 (1977-12-01), Taylor
Borsche et al., Ann, 453, 148 (1927).
Soliman et al., J. Chem. Soc., 1956, pp. 3663-3668.
Eiden et al., Arch. Pharm., 308, 489 (1975).
Schiefer et al., Angew. Chem. Internat. Edit. 4, 527 (1965).
Kirby et al., J. Org. Chem., 28, 2266 (1963).
Hampton et al., J. Org. Chem., 30, 4263 (1965).
Garkusha, Chem. Abstract, 63, 1458d (1965).

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