5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e

Details 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e

1982-07-19

1984-03-06

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424177, 544215, 544374, 260239A, 548464, 560 40, C07D24108, A61K 31495

Patent

active

044355718

ABSTRACT:
The present invention relates to compounds of the formula ##STR1## wherein R' is hydrogen, straight or branched chain lower alkyl having from 1 to 4 carbon atoms or benzyl, Z is hydrogen or straight chain lower alkyl having from 1 to 4 carbon atoms, Y is hydrogen or a nitrogen blocking group selected from the group consisting of tertiary alkoxycarbonyl, benzyloxycarbonyl, cycloalkoxycarbonyl and vinyloxycarbonyl, R.sub.c is hydrogen, halogen or benzyloxy and R.sub.d is hydrogen, or R.sub.c and R.sub.d are benzyloxy; or an individual diastereomer thereof. Said compounds having use as intermediates in the production of enkephalin derivatives which in turn are used as analgesic and antipsychotic agents.

REFERENCES:
patent: 4167512 (1979-09-01), Lai
patent: 4240961 (1980-12-01), Lai
F. Moll and M. Hannig, Arch. Pharm., 303 (10), 831-41 (1970).

Affiliated with

Also associated with

Rating

5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and e will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-742699