5-[Substituted amino methyl]pyrrolo[2,3-d]pyrimidine-4-one

Details 5-[Substituted amino methyl]pyrrolo[2,3-d]pyrimidine-4-one 5-[Substituted amino methyl]pyrrolo[2,3-d]pyrimidine-4-one

1982-09-24

1984-03-06

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424251, C07D48704, A61K 31505

Patent

active

044355696

ABSTRACT:
Novel deazapurine derivatives of the formula: ##STR1## wherein R.sup.1 is C.sub.1-18 alkyl which may be substituted with di-C.sub.1-3 alkyl amino; C.sub.1-18 alkenyl; C.sub.3-8 cyloalkyl; C.sub.5-8 cycloalkenyl; C.sub.7-13 aralkyl which may be substituted with C.sub.1-4 alkoxy, C.sub.1-4 alkanoyl, C.sub.2-4 alkoxycarbonyl, hydroxy, amino, nitro, trifluoromethyl or C.sub.1-4 alkanoylamido; or C.sub.6-10 aryl and

REFERENCES:
patent: 3598824 (1971-08-01), Troxler et al.
patent: 3657245 (1972-04-01), Bormann et al.
patent: 4229453 (1980-10-01), Roth et al.
S. Nishimura et al., GANN Monograph on Cancer Research, 24, 245-262, (1979).
J. R. Katze et al., Biochem. Biophys. Res. Comm., 96, 313-319, (1980).

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