5-Substituted-4-oxo-PGI.sub.1 derivatives, PGI.sub.1 compounds o

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

549214, 549465, 514470, A61K 31557, A61K 31335, C07D307935

Patent

active

045200181

ABSTRACT:
New PGI.sub.1 derivatives are disclosed as well as a process for the preparation thereof, pharmaceutical compositions containing same and methods of treatment employing same. The new compounds are useful to inhibit blood platelet aggregation induced by ADF, arachidic acid, or collagen, as well as to improve blood circulation and to inhibit gastric acid secretion.

REFERENCES:
patent: 4126744 (1978-11-01), Ayer
patent: 4330553 (1982-05-01), Simonidesz et al.
patent: 4430497 (1984-02-01), Vollenberg et al.
patent: 4438132 (1984-03-01), Gatambos et al.

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