5-substituted 3-aminoalkyl indoles

Details 5-substituted 3-aminoalkyl indoles 5-substituted 3-aminoalkyl indoles

1987-08-06

1989-06-13

Ceperley, Mary E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514212, 514323, 514414, 540602, 546201, 548468, 548504, A61K 3140, C07D20916

Patent

active

048393770

ABSTRACT:
Compounds are disclosed of general formula (I) ##STR1## wherein R.sub.1 represents a group CHO, COR.sub.8, CO.sub.2 R.sub.8, CONR.sub.9 R.sub.10, CSNR.sub.9 R.sub.10 or SO.sub.2 NR.sub.9 R.sub.10,

REFERENCES:
Burger, Medicinal Chemistry, Fourth Edition, Part I, pp. 178-182, John Wiley and Sons, N.Y. (1979), RS 403B8.
Ariens, Drug Design, pp. 10 and 11, vol. II (1971), Academic Press, N.Y. (1971).
L. Greene, Protective Groups in Organic Synthesis pp. 223, 250, 251, 263, John Wiley and Sons (1981) N.Y., QD 262 G665.
I. Coates et al., Chem. Abstracts vol. 97, No. 6148d (1982). Indole derivatives and their medicinal use.

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