Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1979-08-09
1981-05-12
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
265239A, 2652452T, 424250, 424263, 424269, 424270, 424273R, 424273P, 544405, 546272, G07D48704, A61K 3140
Patent
active
042671884
ABSTRACT:
Disclosed are 1-carba-pen-2-em-3-carboxylic acids of the following structure: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are, inter alia, independently selected from the group consisting of hydrogen (R.sup.4 is not hydrogen), alkyl, aryl, and aralkyl. Such compounds as well as their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 4153714 (1979-05-01), Ponsford
Cama Lovji D.
Christensen Burton G.
Arno James A.
Lee Mary C.
Levitt Julian S.
Mahon Frank M.
Merck & Co. , Inc.
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