5 step process for preparing certain 2,4-diamino-5-pyrimidine-su

Details 5 step process for preparing certain 2,4-diamino-5-pyrimidine-su 5 step process for preparing certain 2,4-diamino-5-pyrimidine-su

1989-04-05

1990-04-03

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544317, C07D23946, C07D23948

Patent

active

049142038

ABSTRACT:
This invention relates to substituted 5-pyrimidinesulfonamides, pharmaceutically acceptable salts thereof and to processes for synthesis thereof. Other aspects of the invention concern pharmaceutical compositions containing an instant compound as active ingredient and methods of treatment where there is an indicated need for an antihypertensive and/or diuretic agent.

REFERENCES:
patent: 3817998 (1974-06-01), Anderson
patent: 4018929 (1977-04-01), Delarge
patent: 4244950 (1981-01-01), De Ridder
J. Delarge et al, Ann. Pharm. Fr. 32 (12) 657-67 (1974).
J. Delarge et al, Eur. J. Med. Chem.-Chimica Therapeutica 15, 299-304 (1980).

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