Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1982-07-06
1983-12-13
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D40104
Patent
active
044206178
ABSTRACT:
5-PY-6-Q-pyridin-2-amines (I) or pharmaceutically acceptable acid-addition salts thereof are useful cardiotonics, where Q is hydrogen or lower-alkyl, and PY is 4-pyridinyl or 4-pyridinyl having one or two lower-alkyl substituents. Their preparation from the corresponding 5-PY-6-Q-2(1H-pyridinones via the corresponding 2-halo-5-PY-6-Q-pyridines is shown.
REFERENCES:
patent: 4297360 (1981-10-01), Lesher et al.
patent: 4331672 (1982-05-01), Lesher et al.
D. A. Inoyatova et al., [Chem. Absts. 74, 125,360b (1971); Tr. Samarkand. Gos. Univ. 1969, No. 167, 173-174 (Russ.) from Ref. Zh., Khim 1970, Abstr. No. 5Zh482].
Lesher George Y.
Opalka, Jr. Chester J.
Page Donald F.
Bair Robert K.
DuPont Paul E.
Ford John M.
Sterling Drug Inc.
Wyatt B. Woodrow
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