5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the

Details 5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the 5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the

1983-06-20

1985-09-17

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514913, A61K 3138

Patent

active

045421528

ABSTRACT:
5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides are useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.

REFERENCES:
patent: 4029809 (1977-06-01), Smith et al.
patent: 4386098 (1983-05-01), Woltersdorf et al.
Gelatt et al.-Am. J. Vet. Res. 40(3)-334-345 (1979), "Ocular Hypotensive Effects of Carbonic Anhydrase Inhibitors in Normotensive and Glaucomatous Beagles".

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