5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5482632, A61K 3141

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active

049468561

ABSTRACT:
This invention relates to 5-phenyl-3H-1,2,4-triazol-3-ones and to their use as anticonvulsants for treatment of seizure disorders.

REFERENCES:
patent: 3514466 (1970-05-01), Stahle et al.
patent: 4414221 (1983-11-01), Parsons et al.
G. Maffii, et al., Studio Faramacologico di Alcuni Ossadiazoli e Triazoli, Farmaco 13, 629-38 (1958). (Translation Provided).
M. Y. Mhassalkar, et al., Further Studies in Substituted 4H-1,2,4-Triazoles for Possible Hypoglycemic Activity, J. Med. Chem. 14, 1260-3 (1971).
F. P. Miller, et al., FASEB J. 2, A1070, Abstract 4501 (1988).

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