Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-11-29
2005-11-29
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S182000
Reexamination Certificate
active
06969716
ABSTRACT:
The present invention provides a compound of formula I, or an N-oxide thereof or a pharmaceutically acceptable salt thereof:whereinX1represents hydrogen, halogen, C1-6alkyl, trifluoromethyl or C1-6alkoxy;X2represents hydrogen or halogen;Z represents hydrogen, halogen, cyano, cyanomethyl, trifluoromethyl, nitro, hydroxy, hydroxy(C1-6)alkyl, C1-6alkoxy, C1-6alkoxy(C1-6)alkyl, trifluoromethoxy, trifluoromethylthio, trifluoromethanesulfinyl, formyl, C2-6alkoxycarbonyl, oxopyrrolidinyl, or an optionally substituted aryl, heteroaryl or heteroaryl(C1-6)alkoxy group; andR1represents aryl or heteroaryl, either of which groups may be optionally substituted;pharmaceutical compositions comprising it, its use in therapy and methods of treatment of anxiety and/or depression using it.
REFERENCES:
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Blackaby Wesley Peter
Goodacre Simon Charles
Hallett David James
Jennings Andrew
Lewis Richard Thomas
Balasubramanian Venkataraman
Merck Sharp & Dohme Ltd.
Thies J. Eric
Winokur Melvin
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