Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2009-07-06
2011-11-29
Dentz, Bernard (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S282000
Reexamination Certificate
active
08067460
ABSTRACT:
Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).
REFERENCES:
Vennekamp et al, Molecular Pharmacology, vol. 65, No. 9, p. 1364-1374 (2004).
Haensel Wolfram
Sankaranarayanan Ananthakrishnan
Schmidt-Lassen Kristina
Schmitz Alexander
Wulff Heike
Buyan Robert D.
Dentz Bernard
Stout, Uxa, Buyan & Mullins
The Regents of the University of Califonia
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