5-oxygenated HMG-CoA reductase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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549264, 549292, 549216, 549 60, 549 6, 544 57, 544 70, 544 6, 544149, 544374, 544230, 544232, 546 15, 546 22, 546204, 546256, 548517, 548407, 548413, 514460, 514824, 5142278, 5142315, 514255, 514326, 514278, 514409, 514422, 514444, 514459, 514330, A61K 31365, C07D30930

Patent

active

049635387

ABSTRACT:
Novel HMG-CoA reductase inhibitors are useful as antihypercholesterolemic agents and are represented by structural formulae (I) or (II): ##STR1## wherein position 5 of the polyhydronaphthyl ring is singly or doubly bonded to oxygen or incorporated into a C.sub.3-7 carbocyclic ring.

REFERENCES:
patent: 4448979 (1984-05-01), Terahara et al.
patent: 4517373 (1985-05-01), Terahara et al.
patent: 4537859 (1985-08-01), Terahara et al.
patent: 4604472 (1986-08-01), Ide et al.
patent: 4733003 (1986-03-01), Ide et al.

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