5-Oxygenated HMG-COA reductase inhibitors

Details 5-Oxygenated HMG-COA reductase inhibitors 5-Oxygenated HMG-COA reductase inhibitors

1990-06-06

1992-07-14

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514480, 514510, 558198, 560 27, 560 32, 560119, 560255, 560256, A61K 3166, A61K 3122, C07C 69013, C07C27138

Patent

active

051303060

ABSTRACT:
Novel HMG-CoA reductase inhibitors are useful as antihypercholesterolemic agents and are represented by structural formulae (I) or (II): ##STR1## wherein position 5 of the polyhydronaphthyl ring is singly or doubly bonded to oxygen or incorporated into a C.sub.3-7 carbocyclic ring.

REFERENCES:
patent: 4420491 (1983-12-01), Albers-Schonberg et al.
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4450171 (1984-05-01), Hoffman et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4851436 (1989-07-01), Hoffman et al.
patent: 4866093 (1989-09-01), Terahara et al.
Alberts, A. W., American Journal of Cardiology, 62, pp. 105-155 (1988).
Stokker, G. E. et al., J. Med. Chem. 28, pp. 347-358 (1985).

Affiliated with

Also associated with

Rating

5-Oxygenated HMG-COA reductase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-Oxygenated HMG-COA reductase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-Oxygenated HMG-COA reductase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-334745