5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514343, 514423, 514424, 5462784, 5462791, 548537, 548543, 548550, 548551, A61K 314015, A61K 314439, C07D20712, C07D20716, C07D40104

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active

061143618

ABSTRACT:
The present invention relates to a compound of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 are as defined above, to pharmaceutical compositions and methods of treatment.

REFERENCES:
M. Zhao et al., Tetrahedron Letters 1998, No. 39, pp. 5323-5326, A Novel Chromium Trioxide Catalyzed Oxidation of Primary Alcohols to the Carboxylic Acids.
Hidemi Yoda et al., Tetrahedron: Asymmetry 1996, vol. 7, No. 7 pp. 2113-2116, An Expeditious and Practical Synthetic Process for Phytosphingosine and Tetrahydroxy-LCB from D-Glutamic Acid.
Stephane Caron and Joel M. Hawkins, J. Org. Chem. 1998, 63, pp 2054-2055, Directed Ortho Metalation of Neopentyl Benzoates with LDA: Preparation of Arylboronic Acids.
A.H. Fray and A.I. Meyers, J. Org. Chem. 1996, 61, pp 3362-3374, Single and Double Diastereoselection in Azomethine Ylide Cycloaddition Reactions with Unsaturated Chiral Bicyclic Lactams.

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