(5-Oxo-10,11-dihydrodibenzo[a,d]-cyclohepten-2-yl)-alkanoic acid

Details (5-Oxo-10,11-dihydrodibenzo[a,d]-cyclohepten-2-yl)-alkanoic acid (5-Oxo-10,11-dihydrodibenzo[a,d]-cyclohepten-2-yl)-alkanoic acid

1974-02-28

1976-01-20

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268TR, 2603409, 260469, 2605011, 260520, 260558R, 260559D, 424317, C07C 6520

Patent

active

039339050

ABSTRACT:
Dibenzo[a,d]cycloheptene derivatives of the formula: ##SPC1##
Wherein X represents hydrogen, halogen, alkyl, alkoxy, alkylthio or trifluoromethyl, R.sub.1 and R.sub.2 represent hydrogen or alkyl, and R.sub.3 represents hydroxy, alkoxy, 4-(2,2-dimethyl-1,3-dioxolanyl)-methoxy, or a group --NR.sub.4 R.sub.5 in which R.sub.4 and R.sub.5 represent hydrogen, alkyl, hydroxyalkyl or phenyl, or --NR.sub.4 R.sub.5 represents a mononuclear 5- or 6-membered heterocyclic group optionally containing a second hetero atom selected from oxygen, sulphur, and nitrogen which is optionally substituted by alkyl, said alkyl, alkoxy, alkylthio and hydroxyalkyl radicals containing 1 to 4 carbon atoms, are new compounds possessing pharmacological properties, more particularly analgesic, antipyretic and anti-inflammatory properties.

REFERENCES:
andre Allais et al., Chemical Abstracts, Vol. 78, 111018s, (1973).

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