5-Oxime derivatives of milbemycins and veterinary and agricultur

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549264, A61K 31365, C07D49322

Patent

active

045475202

ABSTRACT:
Oxime derivatives of 5-didehydromilbemycins A.sub.3, A.sub.4 and D are represented by the formula: ##STR1## (wherein R.sup.1 represents methyl, ethyl or isopropyl, and R.sup.2 represents hydrogen, lower alkyl, optionally substituted aralkyl or --CH.sub.2 COOR.sup.3, wherein R.sup.3 represents hydrogen or lower alkyl). These and their salts and esters have valuable anthelmintic, acaricidal and insecticidal activity.

REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
patent: 4093629 (1978-06-01), Fisher
patent: 4171314 (1979-10-01), Chabala et al.
patent: 4423209 (1983-12-01), Mrozik

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