5-Oxa-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub

Details 5-Oxa-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub 5-Oxa-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub

1977-08-01

1978-08-01

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560121, 260514D, 260520R, 260520B, C07C17700

Patent

active

041044746

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract 47293U-B DT.-2305044-Q (09-08-73).
Derwent Abst. 18176y/11 BE-846-080 (10-3-77).
Derwent Abst. 6189x/33, DT 2603-172 (5-8-76).
Derwent Abst. 59715x/32, BE 839-533 (1-7-76).
Derwent Atst. 79219x/42, U.S. 3984400 (5-10-76).

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