5-Oxa-11-deoxy-cis-13-PGE.sub.1 , compounds

Details 5-Oxa-11-deoxy-cis-13-PGE.sub.1 , compounds 5-Oxa-11-deoxy-cis-13-PGE.sub.1 , compounds

1977-03-03

1978-10-03

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562503, C07C17700

Patent

active

041185781

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 3932479 (1976-01-01), Bernady et al.

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