5' nucleases derived from thermostable DNA polymerase

Details 5' nucleases derived from thermostable DNA polymerase 5' nucleases derived from thermostable DNA polymerase

1994-06-06

1997-03-25

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435194, C12N 922

Patent

active

056144024

ABSTRACT:
A means cleaving a nucleic acid cleavage structure in a site-specific manner is disclosed. A cleaving enzyme having 5' nuclease activity without interfering nucleic acid synthetic ability is employed as the basis of a novel method of detection of specific nucleic acid sequences.

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