5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and

Details 5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and 5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and

1995-02-09

1996-07-23

Hulina, Amy

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424449, 424468, 424474, 424480, 424490, 424494, 514269, 544255, 544261, A61K 902, A61K 928, A61K 31505

Patent

active

055387349

ABSTRACT:
The present invention refers to the use of 5-methyltetrahydrofolic acid, of 5-formyltetrahydrofolic acid and of their pharmaceutically acceptable salts for the preparation of controlled release pharmaceutical compositions suitable for the use in the therapy of depressive disturbances, in particular major depression, dysthymia or depressive neurosis and not otherwise specified depressive disturbances, independently from folate plasmatic levels, and to the pharmaceutical composition thus prepared.

REFERENCES:
patent: 4834985 (1989-05-01), Elger et al.
patent: 4959472 (1990-09-01), Wood et al.
patent: 5059595 (1991-10-01), Le Grazie
Botez et al, "Folate Deficiency and Decreased Brain 5 Hydroxy-tryptamine Synthesis in Man and Rat", Nature, vol. 278, Mar. 8th 1979, p. 182.
Manzoor et al, "Folak-Responsive Neuropathy: Report of 10 Cases", British Medical Journal, 15 May 1976, p. 1176.
Reynolds et al, "Effects of Folic Acid On the Mental State and Fit-Frequency of Drug-Treated Epileptic Patients", The Lancet, May 20, 1967.
Drug Information for the Consumer United States Pharma-Copeial Convention, Inc., Eighth Edition, 1988, p. 662.

Affiliated with

Also associated with

Rating

5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-methyltetrahydrofolic acid, 5-formyl-tetrahydrofolic acid and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-711366