Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-07-21
1988-06-07
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514250, 5142298, A61K 3150, A61K 3154, A61K 31495
Patent
active
047496991
ABSTRACT:
Compounds of the Formula I: ##STR1## are inhibitors of the mammalian 5-lipoxygenase enzyme system of the arachidonic acid cascade. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.
REFERENCES:
patent: 3746707 (1983-07-01), Gulbenk et al.
patent: 3821213 (1974-06-01), Tong
patent: 3845044 (1974-10-01), Tong
patent: 4552874 (1985-11-01), Mardin et al.
Carter, Chemical Abstracts, vol. 87 (1977) 152146m.
Cheeseman et al, Tetrahedron, vol. 36 (1980), pp. 2681-2683.
Okafor, J., Het. Chem., vol. 18 (1981), pp. 405-407.
Atkinson Joseph G.
Belanger Patrice C.
Guindon Yvan
Rokach Joshua
Friedman Stanley J.
Lopez Gabriel
Merck Frosst Canada Inc.
Pfeiffer Hesna J.
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