5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols

Details 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols

1989-01-12

1990-06-05

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142272, 5142288, 514241, 514242, 514255, 544 55, 544 96, 544182, 544219, 544220, 544230, 544295, 544366, 544367, 544369, 544370, 544371, 544372, 544392, 544393, A61K 31495, C07D40310, C07D41310, C07D41710

Patent

active

049314440

ABSTRACT:
4-(4-phenyl-1-piperazinyl)phenols for use as 5-lipoxygenase inhibitors and a method of treating warm-blooded animals suffering from leukotriene mediated diseases and disorders using the same. Pharmaceutical compositions containing the same as active ingredient. Novel compounds used in said method and processes for preparing said novel compounds.

REFERENCES:
patent: 3720690 (1973-03-01), King et al.
patent: 4144346 (1979-03-01), Heeres et al.
patent: 4267179 (1981-05-01), Heeres et al.
patent: 4335125 (1982-06-01), Heeres et al.
patent: 4368200 (1983-01-01), Heeres et al.
patent: 4503055 (1985-03-01), Heeres et al.
patent: 4619931 (1986-10-01), Heeres et al.
King et al., Chemical Abstracts 79-32066y (1973).
Kiyoura et al., Chemical Abstracts 87-102378t (1977).

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