Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-03-22
1996-04-16
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546322, C07D21384, C07D21380
Patent
active
055084133
ABSTRACT:
This invention relates to novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
More particularly, it relates to novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, which has pharmacological activities such as hypotensive and vasodilating activities, to a pharmaceutical composition comprising the same and to a method for treating hypertension, cardiovascular diseases, and the like.
Accordingly, one object of this invention is to provide novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, which is of use for treating hyperxtension, cardiovascular diseases, and the like.
REFERENCES:
patent: 4284634 (1981-08-01), Sato
patent: 4338322 (1982-07-01), Sato
Jacques et al., Enantiomers, Racemates, And Resolutions, pp. 251-263 Wiley-Interscience Publishers (1981).
Jacques et al., Enantiomers, Racemates and Resolutions, pp. 251-263, Wiley-Interscience publishers 1983.
Okumura Kazuo
Shiokawa Youichi
Fujisawa Pharmaceutical Co. Ltd.
Rotman Alan L.
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