5-Iodo-6-oxo-3-(2'-arylmethoxy-1'-hydroxyethyl)-4-hydroxy-hexano

Details 5-Iodo-6-oxo-3-(2'-arylmethoxy-1'-hydroxyethyl)-4-hydroxy-hexano 5-Iodo-6-oxo-3-(2'-arylmethoxy-1'-hydroxyethyl)-4-hydroxy-hexano

1977-04-04

1978-06-13

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30732

Patent

active

040948838

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 (11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxy derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
corey et al., Chem. Abst., vol. 83, 1975.

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