5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla

Details 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla

1993-08-06

1994-09-20

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514269, A61K 31535, A61K 31495, A61K 31505

Patent

active

053489578

ABSTRACT:
The present invention compounds are 5-hydroxy-2-pyrimidinylmethylene derivatives and pharmaceutically acceptable addition salts, bases, and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of, for example, inflammation and GI ulcers.

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