5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla

Details 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinfla

1992-07-07

1993-12-14

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544121, 544122, 544298, 544333, A61K 31505, C07D40306

Patent

active

052703193

ABSTRACT:
The present invention is novel compounds which are 5-hydroxy-2-pyrimidinylmethylene derivatives and pharmaceutically acceptable addition salts, bases, and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of, for example, preferably inflammation.

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