5-HT.sub.4 agonists and antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546126, A61K 3144, C07D45104

Patent

active

061178829

ABSTRACT:
Compounds of formula I: ##STR1## are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.

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Robert W. Hamilton, J. Heterocyclic Chem., 13, 545-553 (1976).
Kaumann, et al., Bio. Med. Chem. Let., 2, 419-420 (1992).
Derwent Abstract, Belgium 770068 (1970).
Derwent Abstract, Japanese 8081-858 (1972).

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