5-HT.sub.2 receptor antagonist compositions useful in treating v

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514254, 514255, 514317, 514357, A61K 31495, A61K 31445, A61K 3144

Patent

active

056059027

ABSTRACT:
Methods of employing compositions containing 5-hydroxytryptamine-2 (5-HT.sub.2) receptor antagonists for the treatment of such venous conditions as varicose veins, venous insufficiency and wounds are disclosed.

REFERENCES:
patent: Re30811 (1981-12-01), Dykstra
patent: Re30812 (1981-12-01), Dykstra
patent: 3931195 (1976-01-01), Dykstra
patent: 4000143 (1976-12-01), Dykstra
patent: 4064254 (1977-12-01), Dykstra et al.
patent: 4202825 (1980-05-01), Taya
patent: 4265887 (1981-05-01), Breskman
patent: 4335127 (1982-06-01), Vandenberk
patent: 4338317 (1982-07-01), Temple
patent: 4342870 (1982-08-01), Kennis
patent: 4411901 (1983-10-01), Temple, Jr. et al.
patent: 4487773 (1984-12-01), Temple, Jr. et al.
patent: 4539318 (1985-09-01), Bazdwin
patent: 4626433 (1986-12-01), Gros
patent: 4665075 (1987-05-01), Vandenberk
patent: 4677104 (1987-06-01), New
patent: 4985257 (1991-01-01), Verde
patent: 5196405 (1993-03-01), Packman
patent: 5234914 (1993-08-01), Gallina
patent: 5266571 (1993-11-01), Amer
patent: 5403867 (1995-04-01), Okumura
Persson, et al. Journal of Hypertension 1986, 4 (Suppl. 1) 599-5101.
Persson, B. J. Pharm. Pharmacol. 1982 34:442-445.
Kalkman, H. O. et al. Journal of Pharmacology and Experimental Therapeutics, vol. 222 No. 1 1982 pp. 227-231.
Fagard, R. et al. British Heart Journal 1984 vol. 51, 149-56.
Wenting, G. J. Hypertension vol. 6. No. 1 Jan.-Feb. 1984, pp. 100-109.
Humphrey, P. P. A. J. Pharm. Pharmacol. 1982, 34:541.
Van Nueten et al. the Journal of Pharmacology and Experimental Therapeutics vol. 218 No. 1 1981, pp. 217-230.
Hedner, T. Journal of Cardiovascular Pharmacology 11(Suppl. 1): 544-548, 1988.
Van Nueten, J. Journal of Cardiovascular Pharmacology 11(Supp. 1) 5:10-515, 1988.
Cohen, M. L. et al. Hypertension vol. 5. No. 5 Sep.-Oct. 1983 pp. 676-681.
Fozard, J. R. Cardiovascular Pharmacology vol. 4, No. 5, 1982, pp. 829-838.
Hedner, T. Journal of Cardiovascular Pharmacology 7(Suppl. 7)5:148-5153 1985.
Roelens, P., `Double-blind placebo-controlled study . . . ` Dermatogica, vol. 178, 1989, pp. 98-102.
Rooman, R. P. et al. `Ketanserin promotes wound . . . ` Prog. Clin. Biol. Res., vol. 365, 1991, pp. 115-128.
P. A. van Zwieten, et al. "Pathophysiological and Pharmarco Therapeutic . . . " Clin. Physiol Biochem 1990-(Suppl 3:1-18).
Frazer, A. et al. "SugTypes of Receptors for Serotonin" Annu. Rev. Pharmacol. Taxicol, 1990. 307-348.
Chsuhing, D. J. "Comparison of the Serotonin . . . " Journal of Pharmacology and Experimental Therapeutics vol. 261 pp. 856 1992.
Shoji, T. et al. "Renal Vasodilatation" . . . European Journal of Pharmacology 190(1990) 247-250.
M uller-Schweinitzer, E. "Venoconstrictor Responses . . . " Cardiovascular Drugs and Therapy 1940;4:1455-1460 (1990).
Heuven-Nolsen, D. V. "5-HT1-like receptors" European Journal of Pharmacology, 191(1990) 375-382.
Blauw, G. J. "Antihypertensive Treatment . . . " Drugs 40(Suppl.4) 42-44, 1990.
Persson, B. "Antihypertensive Effects . . . Journal of Cardiovascular Pharmacology" (Suppl.1) 522-524, 1988.
Radic, Z. J. "Alterations in Serotonergic . . . " Journal of Vascular Surgery 40-47, 1991.
Sahin-Erdemli, I. "5-HT-like receptors . . . " Br. J. Pharmacol 1991, 386-390 (1990).
Alsip, N. L. "Multiple Serotonin . . . " Blood Vessels 1991; pp. 537-541.
Van Zwieten, P. A. "Pharmacological Profile . . . " Drugs 40(Suppl. 4):1-8, 1990.
Zhang, U. "Charcterization of Serotonergic . . . " Journal of Pharmacology and Experimental Therapeutics. 233-239 (1989).
Prichard, B. N. C. et al. "Serotorin :Receptors . . . " Clin Physiol Biochem, 1990 :8 (Suppl 3):120-128.
Summer, M. J. "Characterization of 5-HT . . . " Br. J. Pharmacol. (1991) 102.938-942.
DaGaire, H. "Haemodynamic Aspects . . . "Clin Physiol Biochem 1990:8(Suppl 3) 56-63.
Lai, F. M. et al. "Characterization of Serotonin . . . The Journal of Pharmacology and Experimental Therapeutics," 164-168 (1990).
Van Zwieten, P. A. et al. "The role of 5-hydroxytryptamine . . . " Br. J. Clin. Pharmac. (1990)30 695-745.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

5-HT.sub.2 receptor antagonist compositions useful in treating v does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-HT.sub.2 receptor antagonist compositions useful in treating v, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-HT.sub.2 receptor antagonist compositions useful in treating v will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1974121

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.